Close on 09 Oct 2026
All US Equities (S&P 500 / NASDAQ-100)

Alnylam Pharmaceuticals

ALNYUS Listed
Exchange: NASDAQ · Market: US Equities · Currency: USD

Alnylam Pharmaceuticals (ALNY) is a leading publicly traded corporation listed in the United States, constituent of the NASDAQ-100 index.

Sector: Health Care·Indices: NASDAQ-100·Market Cap: $30.38B
Close on 16 Oct 2026
$231.83
-2.20 (-0.94%)
Last updated: 16 Oct 2026 (US Market EOD settlement)

Stock Snapshot & Key Numbers — Alnylam Pharmaceuticals

Verified Daily Close

Official closing price, 1-year price range, valuation multiples, and market value from exchange records.

Last Session Move
Down -0.94% on 16 Oct 2026
Position vs 1-Year High
52.8% below 52W High
P/E Valuation Multiple
38.3x (20x–40x range)
Annual Cash Dividend
0.00% / No Recent Dividend
Close on 16 Oct 2026
$231.83
-2.20 (-0.94%)vs prev close
1-Year Low to High Range9% of range
Low: $205High: $491
Valuation (P/E, P/B & Dividend)
P/E Ratio (Price / Profit):38.3x
P/B Ratio (Price / Book):22.4x
Dividend Yield:N/A
Total Company Value (Market Cap)
$30.38B
Sector: Health Care
Latest Official Announcement:Alnylam Securities Probe Continues After $200M Guidance Cut Triggers Share Slump - scanx.trade
3d ago
Plain-English Company Summary

Alnylam Pharmaceuticals (ALNY) is a US equity security listed on the NASDAQ. As of the last recorded market session on Close on 16 Oct 2026, the stock closed at $231.83, recording a -2.20 (-0.94%) decline from its previous close of $234.03. Over the trailing 52-week trading cycle, ALNY has traded between a 52-week low of $205.48 and a 52-week high of $491.22, establishing its annual trading channel. In historical performance, Alnylam Pharmaceuticals has fallen 51.81% over the past 1 year. Period returns across standard measurement intervals include: 1-week: -0.37%, 1-month: -3.15%, 6-month: -27.58%, 1-year: -51.81%, 3-year: +38.61%, 5-year: +13.7%. Daily reported trading volume reached 1,404,800 equity shares. On key valuation multiples as of Oct 13, 2026, the company trades at a trailing price-to-earnings (P/E) multiple of 38.3x and a price-to-book (P/B) ratio of 22.4x, with a trailing dividend yield of data unavailable. Its market capitalization stands at $30.38B. The company is categorized under the Health Care sector and NASDAQ-100 industry within the US equities universe.

Price Chart

1Y: -51.81% (₹-249.24)
₹491₹394₹300₹205Thu, 16 Oct, 2025Fri, 16 Oct, 2026

Trading Multiples & Ranges

Price boundaries and liquidity distribution.

52-Week Range$205.48 – $491.22
Low: $205.48High: $491.22
$205.48$491.22
Trailing P/E Ratio38.28x
Price to Book (P/B)22.42x
Dividend Yield0.00%
Day High / Low$231.29 – $237.98
Daily Volume1.40M

Past Price Win/Loss Odds (1-Week, 1-Month, 3-Month)

How often this stock rose, stayed flat, or fell over past 21-day holding periods (based on historical data, not a future prediction).

1 Month Holding Period (21 trading days)
1,234 past 21-day periods analyzed
Fell 32.8%
Within ±5% (36.5%)
Rose 30.7%
Fell > 5%
32.8%
405 windows
Within ±5%
36.5%
450 windows
Rose > 5%
30.7%
379 windows
In 80% of past 1 month windows the move was within ±14.2%.
Historical outcomes of this stock's own price. Not a forecast. (1255 trading days of history).
How to read historical odds

At-a-Glance Health & Momentum Check

Market Mood: Consolidation / Rangebound
News Activity
STABLE
Recent announcement pace
Profit & Margin Trend
CONTRACTING
Earnings & margin direction
Economy Sensitivity
MODERATE
Impact of rates, oil & FX
Broad Market Mood
Consolidation / Rangebound
Current market trend
News Tone
NEGATIVE SCRUTINY
Recent filing tone
What This Means(based on reported financials)

While recent announcements reflect past operations, profit margins and return on capital have been tightening as the business absorbs higher costs or new expansion spending.

Active Risk Flags & Monitoring Constraints
Standard systemic equity market and interest rate cycle exposure

How Outside Factors Affect This Stock (Market, Crude Oil & Currency)

How closely this stock moved with the broader market index, crude oil, and the exchange rate over the past year.

Swing Rank: 50th percentile
Typical 1-Year Price Swing (Volatility): 51.5% annualized
Price Swing Level vs Market: Moderate Swings
Factor / Benchmark1Y Beta (Sensitivity)1Y Correlation (-1 to +1)What This Means
S&P 500+0.42+0.10Trailing 1Y historical sensitivity: a 1% move in S&P 500 coincided with a +0.42% co-movement (correlation: 0.10). Descriptive historical relationship, not predictive.
US 10Y Treasury Yield-0.62-0.17Trailing 1Y historical sensitivity: a 1% move in US 10Y Treasury Yield coincided with a -0.62% co-movement (correlation: -0.17). Descriptive historical relationship, not predictive.
Brent Crude Oil-0.09-0.09Trailing 1Y historical sensitivity: a 1% move in Brent Crude Oil coincided with a -0.09% co-movement (correlation: -0.09). Descriptive historical relationship, not predictive.
USD / INR+0.36+0.05Trailing 1Y historical sensitivity: a 1% move in USD / INR coincided with a +0.36% co-movement (correlation: 0.05). Descriptive historical relationship, not predictive.
How to read Beta & Correlation ( Beta > 1 = wider swings than market; < 1 = calmer )▾

Sensitivities measure historical 1-year regression beta and correlation across paired daily trading sessions over the past 252 trading days. Past relationships can shift over time and do not guarantee future co-movement.

Trailing Returns Breakdown

Calendar-aligned historical percentage performance across standard market windows.

PeriodStart PriceCurrent PriceReturn (%)
1 Week₹232.68₹231.83-0.37%
15 Days₹231.18₹231.83+0.28%
1 Month₹239.36₹231.83-3.15%
3 Months₹283.15₹231.83-18.12%
6 Months₹320.13₹231.83-27.58%
1 Year₹481.07₹231.83-51.81%
3 Years₹167.25₹231.83+38.61%
5 Years₹203.90₹231.83+13.70%

Price Swings & Biggest Historical Drops

How much this stock typically fluctuates and its largest peak-to-bottom drops over 1 and 5 years.

1Y Yearly Swing
51.5%
Annualized volatility
1Y Beta vs Index
0.47
vs benchmark index
Biggest 1Y Drop
-58.2%
1Y peak-to-low drop
Biggest 5Y Drop
-58.2%
5Y peak-to-low drop
vs 52W High
-52.8%
Distance from 1Y high
vs 52W Low
+12.8%
Gain above 1Y low

Calendar-Year Historical Performance

Annual performance breakdown comparing first and last closing sessions of each calendar year.

Calendar YearStart CloseEnd CloseAnnual ReturnTrajectory Bar
CY 2026₹400.17₹231.83-42.1%
CY 2025₹233.62₹397.65+70.2%
CY 2024₹194.93₹235.31+20.7%
CY 2023₹233.59₹191.41-18.1%
CY 2022₹173.91₹237.65+36.6%
CY 2021₹203.90₹169.58-16.8%

Corporate Actions History

No dividend or stock split distributions recorded in historical feeds for ALNY.

Historical Investment Simulator

Factual simulation of past returns in Alnylam Pharmaceuticals (ALNY) using real recorded closing prices.

₹1,00,000.00
5 Years
Principal Invested
₹1,00,000.00
₹1,00,000.00 starting capital
Portfolio Value Today
₹1,13,697.90
Based on latest close
Absolute Return
+13.7%
+₹13,697.90
Annualized (CAGR)
+2.6%
Compound annual growth
Entry Price: ₹203.90 · Exit Price: ₹231.83
Simulated 5Y period (INR)

Recent News & Official Exchange Announcements

Official exchange filings, order wins, and company updates. Click any announcement to see how it affects the business on the right.

Showing 1 of 1 Updates
#1 REGULATORY POLICYLODR Materiality: 88/100Business HeadwindRecent Event
3d ago

Alnylam Securities Probe Continues After $200M Guidance Cut Triggers Share Slump - scanx.trade

Alnylam Securities Probe Continues After $200M Guidance Cut Triggers Share Slump scanx.trade

Valuation Impact:-2.5% to -5.5% (Regulatory Scrutiny Risk Premium)
Inspecting in Causal Panel
Source: scanx.trade·Horizon: IMMEDIATE
SEBI LODR Reg 30 Mapped

Why This Matters for the Business

Plain-English breakdown of how the selected announcement connects to revenue, costs, and business drivers.

Causal Attribution in Focus
REGULATORY POLICY·3d ago
Verified Exchange / Wire Disclosure:
Alnylam Securities Probe Continues After $200M Guidance Cut Triggers Share Slump - scanx.trade
Source: scanx.trade·LODR Materiality: 88/100Headwind
3-Stage Transmission Mechanism:
1. Disclosure Trigger
Regulatory & Corporate Disclosure Event
2. Sector Transmission
Sector-wide volume demand absorption & operating leverage
3. ALNY Accretion
-2.5% to -5.5% (Regulatory Scrutiny Risk Premium)
Causal Attribution Analysis:Primary Value-Chain Beneficiary

Statutory authority initiated administrative review or penalty demand, increasing contingent liabilities.

Extracted Factual Evidence:
  • •Statutory authority or regulatory body issued show cause or demand notice
P&L Operating Leverage

Volume throughput absorbs fixed manufacturing plant overheads, supporting operating EBITDA margins and cash generation across health care units.

Order Book & Revenue Visibility

Continuous commercial tenders and capital expenditures lock in forward order book-to-bill expansion.

Affected Financial Metrics:
Regulatory ComplianceLegal ContingenciesOperational Continuity
Cross-asset macro betas (Brent Crude, USD/INR, NIFTY) are mapped in the dedicated dependency engine.
View Graph
Evidence Integrity: Hypotheses and attribution models are anchored strictly in verified regulatory disclosures, public tenders, and audited financial statements across a trailing 6-month capital cycle.

Common Questions About Alnylam Pharmaceuticals (ALNY)

Key facts on ALNY share price, historical returns, valuation ratios, and past SIP performance.

What is the current share price and 52-week range of Alnylam Pharmaceuticals (ALNY)?

As of 16 Oct 2026, the official closing share price of Alnylam Pharmaceuticals (ALNY) on NASDAQ is $231.83 (-0.94% vs the previous close). Over the past 52 weeks, ALNY has traded between a low of $205.48 and a high of $491.22, with a reported market capitalization of $30.38B.

What are the historical returns of Alnylam Pharmaceuticals (ALNY)?

Based on split-adjusted closing prices through 16 Oct 2026, Alnylam Pharmaceuticals (ALNY) recorded the following trailing price returns: 1 Week: -0.37% (from $232.68 to $231.83); 15 Days: +0.28% (from $231.18 to $231.83); 1 Month: -3.15% (from $239.36 to $231.83); 3 Months: -18.12% (from $283.15 to $231.83); 6 Months: -27.58% (from $320.13 to $231.83); 1 Year: -51.81% (from $481.07 to $231.83); 3 Years: +38.61% (from $167.25 to $231.83); 5 Years: +13.70% (from $203.90 to $231.83). Past performance reflects historical exchange records and does not predict future returns.

What is the P/E ratio, P/B ratio, and dividend yield of Alnylam Pharmaceuticals (ALNY)?

Alnylam Pharmaceuticals (ALNY) currently trades at a trailing Price-to-Earnings (P/E) ratio of 38.3x, a Price-to-Book (P/B) ratio of 22.4x, and a trailing 12-month dividend yield of not reported. It operates in the Health Care sector (NASDAQ-100).

How much would a past lump-sum or monthly SIP investment in ALNY have grown?

Based on historical closing prices for Alnylam Pharmaceuticals (ALNY): A one-time lump-sum investment of $10000.00 held for 5 years would be worth $11369.79 (+13.7% total return, 2.6% CAGR), while a monthly SIP of $500.00 over 5 years (total invested: $30500.00) would be worth $32952.34 (+8.0% absolute return). You can test custom amounts and holding periods in the interactive calculator above.